Recognizing the Red Flags: Signs that Your UTI Might be Getting Worse

Urinary tract infections (UTIs) are common bacterial infections that can cause discomfort and disrupt your daily life. While most UTIs can be effectively treated with antibiotics, it's important to be aware of signs that may indicate a worsening infection. By recognizing these red flags, you can seek prompt medical attention and prevent potential complications. In this blog post, we will discuss the signs that a UTI might be getting worse, helping you stay informed and proactive about your health.

What are signs that a UTI is getting worse?

Persistent or Worsening Symptoms:

One of the primary indicators that a UTI is getting worse is when the symptoms persist or intensify despite starting treatment. If you've been taking prescribed antibiotics for a few days and notice that your symptoms, such as urinary urgency, frequency, or pain, are not improving or are worsening, it's essential to contact your healthcare provider.

Fever and Chills:

While not all UTIs are accompanied by a fever, an increasing body temperature, and chills can be warning signs of a more severe infection. If you develop a high fever (generally above 100.4°F or 38°C) along with your UTI symptoms, it could indicate that the infection has spread to the kidneys or beyond, requiring immediate medical attention.

Flank Pain:

Flank pain refers to discomfort or tenderness in the area below the ribs and above the hip, on either side of the back. If you experience worsening or new-onset flank pain in addition to your UTI symptoms, it may suggest a kidney infection (pyelonephritis). Kidney infections can be more serious and require prompt medical evaluation and treatment.

Blood in Urine:

Hematuria, the presence of blood in the urine, can be a sign of a more severe UTI or other underlying issues. If you notice pink, red, or brown discoloration in your urine, it's crucial to seek medical attention promptly. While it can be alarming, remember that blood in the urine does not always indicate a serious condition, but it should be evaluated by a healthcare professional.

Strong Odor or Cloudy Urine:

If your urine has a strong, foul odor or appears cloudy, it could suggest a worsening UTI. These changes may indicate a higher concentration of bacteria or the presence of pus in the urine, which requires medical attention.

Increased Urinary Urgency or Incontinence:

If you experience a sudden increase in urinary urgency or episodes of urinary incontinence, it could signify a worsening UTI. The feeling of needing to urinate frequently, but passing only small amounts of urine, may also be a cause for concern.

Generalized Malaise and Fatigue:

As a UTI progresses, you may experience a general sense of malaise, fatigue, or weakness. These symptoms could indicate that the infection is spreading or affecting your overall well-being.

Nausea, Vomiting, or Loss of Appetite:

In more severe cases of UTIs, the infection can cause systemic symptoms beyond the urinary system. If you develop persistent nausea, vomiting, or a loss of appetite in conjunction with your UTI symptoms, it may signal a more extensive infection. These symptoms may be associated with kidney involvement and necessitate immediate medical attention.

Fatigue and Mental Fogginess

While fatigue and mental fogginess are general symptoms that can occur with various conditions, they can also manifest as a UTI worsens. If you experience prolonged fatigue, difficulty concentrating, or mental confusion along with your UTI, it could indicate a more significant infection affecting your overall well-being.

Rapid Onset of Symptoms:

In some cases, a UTI can progress rapidly, leading to a sudden onset of severe symptoms. If you experience a swift escalation of symptoms, such as intense pain, high fever, confusion, or rapid deterioration in your overall condition, it could be a sign of a severe infection or urinary obstruction. Seek immediate medical attention in such situations.

How to Treat a UTI

Treating a urinary tract infection (UTI) typically involves a combination of self-care measures and medical treatment. Here's a general guide on how to treat a UTI:

  • Drink plenty of water: Staying hydrated can help flush out bacteria from your urinary tract. Aim to drink at least eight 8-ounce glasses of water a day.
  • Urinate frequently: Don't hold in your urine. Urinate when you feel the urge to do so, as this can help to flush out bacteria.
  • Avoid irritants: Stay away from alcohol, caffeine, spicy foods, and citrus juices, as they can irritate your bladder and worsen your symptoms.
  • Use a heating pad: Applying a heating pad to your abdomen can help to alleviate discomfort caused by UTI symptoms.
  • Over-the-counter pain relievers: Nonprescription pain relievers such as ibuprofen (Advil, Motrin IB) or acetaminophen (Tylenol) can help to alleviate pain and discomfort associated with a UTI.
  • Cranberry products: Some studies suggest that cranberry juice and other supplements may help prevent UTIs, but their effectiveness in treating UTIs is still unclear. If you find cranberry products helpful, you can incorporate them into your treatment plan.
  • Antibiotics: If your symptoms persist or worsen, your healthcare provider may prescribe antibiotics to treat the underlying bacterial infection. It's crucial to take the full course of antibiotics as prescribed, even if your symptoms improve before you finish the medication.

Preventive Measures

After completing treatment, consider preventive measures to reduce your risk of recurrent UTIs. These may include staying hydrated, practicing good hygiene, urinating after intercourse, and avoiding irritants that can trigger UTIs.

When to Seek Medical Attention

While UTIs are common in women and often respond well to treatment, it is important to be aware of signs that a UTI may be getting worse. Increased lower abdominal pain, recurrence of symptoms after completing antibiotics, changes in urinary habits, nausea, vomiting, loss of appetite, fatigue, mental fogginess, night sweats or can't sleep at night, and rapid onset of severe symptoms are all potential indicators of a worsening UTI.

If you notice any of these signs, promptly contact your healthcare provider to ensure appropriate evaluation, treatment, and prevention of complications. Remember, proactive management and early intervention are crucial for resolving UTIs effectively and safeguarding your well-being.

Common Questions About UTIs

Does ejaculating make a UTI worse?

Ejaculation itself does not directly exacerbate a urinary tract infection (UTI), but sexual activity, including ejaculation, can contribute to UTIs by introducing bacteria from the genital area into the urethra, particularly during activities involving penetration. This risk is heightened when individuals delay urination after sex, allowing bacteria to multiply in the urinary tract.

Additionally, friction during sexual activity may irritate the urinary tract, potentially increasing susceptibility to infection. To mitigate these risks, it's crucial to maintain good hygiene, stay hydrated, urinate promptly after sexual activity, and practice safe sex. If UTI symptoms arise, such as pain or burning during urination, frequent urination, or cloudy or bloody urine, seeking medical evaluation and treatment promptly is important.

Will my period make my UTI worse?

Having your period itself doesn't typically make a urinary tract infection (UTI) worse. However, some individuals may experience increased discomfort or confusion between UTI symptoms and menstrual symptoms due to overlapping symptoms such as pelvic pain or frequent urination.

Menstruation doesn't directly influence the development or progression of UTIs, but it's essential to manage both conditions effectively to minimize discomfort and prevent complications. Maintaining good hygiene, changing sanitary products frequently, and staying hydrated can help alleviate symptoms and promote overall urinary tract health during your period.

Can prednisone make a UTI worse?

Prednisone, a corticosteroid medication, is not typically known to directly exacerbate urinary tract infections (UTIs). However, prednisone can weaken the immune system and mask some of the symptoms of infection, which may potentially delay diagnosis and treatment.

Additionally, corticosteroids can increase blood sugar levels, and if you have diabetes, uncontrolled blood sugar levels can predispose you to infections, including UTIs. Therefore, it's essential to monitor your symptoms closely and communicate with your healthcare provider if you're taking prednisone and suspect you have a UTI.

Does alcohol make a UTI worse?

Alcohol itself doesn't directly worsen a urinary tract infection (UTI). However, alcohol can irritate the bladder and potentially exacerbate UTI symptoms such as urinary urgency and frequency. Alcohol consumption may also impair your immune system's ability to fight off the infection, delaying recovery. Additionally, alcoholic beverages can lead to dehydration, which can concentrate urine and irritate the bladder further.

It's generally advisable to limit or avoid alcohol consumption while you have a UTI to help alleviate symptoms and support your body's ability to heal. Staying hydrated with water is especially important during this time.

Can you have sex while on antibiotics for UTI?

It's generally advisable to avoid sexual activity while you're being treated for a urinary tract infection (UTI) with antibiotics. Here's why:

  • Potential Spread of Infection: UTIs are often caused by bacteria, and sexual activity can potentially spread these bacteria to your partner, even if you're taking antibiotics.
  • Increased Discomfort: UTIs can cause discomfort and pain, especially during sexual activity. Antibiotics may help alleviate symptoms, but it's best to give your body time to heal fully before engaging in sexual activity to avoid exacerbating any discomfort.
  • Antibiotic Efficacy: Antibiotics work best when taken as prescribed and given the time to effectively combat the infection. Engaging in sexual activity may interfere with the antibiotic's ability to clear the infection.


The attentive, compassionate physicians, providers, and staff at Adult Pediatric Urology & Urogynecology are committed to providing innovative, quality patient care in our state-of-the-art facility.

From screening and prevention to treatment and recovery, our health professionals will be there for you. Our team of dedicated physicians has been serving residents of Nebraska, Iowa, and South Dakota for more than 25 years.

Contact us today